Angelica Sinensis root extract powder

• Product Detail

 

Product name	Angelica Sinensis root extract powder
Latin Name	Angelica Sinensis (Oliv.)Diels
Active ingredients	Ligustilides
synonyms	Dang Gui,Angelica Sinensis, angelica extract, angelica root , chinese angelica, female ginseng, Angelica Sinensis root Root, tang kuei, Radix Angelicae Sinensis, women’s ginseng
Appearance	Brown fine powder
Part used	Root
Specification	Ligustilide 1% HPLC/20:1 TLC
Dosage	1-2g
Main benefits	Women’s health, menopause health
Applied industries	Bodybuilding, women’s health, healthcare supplement

What is Angelica Sinensis root extract powder?

Dang Gui,known as Chinese Angelica, is a Chinese Herb of the Umbelliferae plant family.Before I wrote this article, I am not sure which names to act as the title since there are so may names for Angelica Sinensis root. As a Chinese, in domestic market, we use Dang Gui root instead. After searching google keyword tools, we found Angelica Sinensis root is the most popular for angelica sisnensis, while angelica sinsnensis is the latin name for it.

Angelica Sinensis root comes in tablet, liquid extract, and raw root forms. In Chinese medicine, Angelica Sinensis root is often boiled or soaked in wine. The root is removed and the liquid is taken orally. Angelica Sinensis root is also known as Chinese Angelica and is primarily known for it's uses in treating women's problems including lack of sexual desire, the symptoms of menopause, cramps and PMS. It aids in increasing the effects of hormones in both men and women and is widely used as an aphrodisiac. Angelica Sinensis root is particularly useful in helping to end hot flashes and menstrual cramps. It is also used as a liver tonic and in treating sciatica and shingles. It is one of the most widely consumed herbs in China, used as frequently as ginseng and licorice. Angelica Sinensis root has been used by the Chinese for more than two thousand years, as a strengthener of the heart, lung, spleen, liver and kidney meridians and as a tonic for the blood. It is traditionally characterized as a warm atmospheric energy that promotes blood circulation.

History of Angelica Sinensis root extract powder

Angelica Sinensis root is the dried and sliced root of Chinese Angelica, a sturdy perennial plant that is native to China and Japan, and when cultivated, may reach a height of up to six feet, bearing bright green leaves and clusters of white flowers.  Both the Chinese species(Angelica sinensis) and Japanese species (Angelica acutiloba) have have very similar therapeutic effects, although each country claims to produce the superior Angelica Sinensis root.  In Asia, the plant has been cultivated for thousands of years for medicinal purposes and was first recorded in 588 B.C., for the treatment of painful menstruation. Often referred to as the Female Ginseng, it has been used to treat a wide variety of disorders, particularly "female" disorders, and in the Orient, Angelica Sinensis root is second only in reputation and sales to ginseng and licorice root.  Chinese and Japanese herbalists have also used Angelica Sinensis root for the prevention and treatment of allergic symptoms in individuals who are sensitive to a variety of substances, such as pollen, dust, animal dander, foods, etc.  Chemical constituents of Angelica Sinensis root include coumarins, essential oils, vitamins B-1, B-2, B-5 and vitamin C, beta-carotene, acids, calcium, iron, magnesium, manganese, zinc, phosphorus, potassium selenium, flavonoids and phytoestrogens (characterized by both high and low estrogen levels, which may account for much of the plant's use to regulate competing actions).

chemical constituents of Angelica Sinensis root extract powder

Angelica Sinensis root contains essential oil (0.4-0.7%) consisting of 45% ligustilide, n-butylphthalide, cadinene, carvacrol, safrole and isosafrol. The root also contains sucrose (40%) and various lactonesand vitamins, together with phytosterols, ferulic acid and coumarins, including osthole, psoralen and bergapten. Ferulic acid and ligustilide are considered to be the main active components and it has been suggested that assessment of total ferulic acid content provides a good measure of herbal quality.The active constituents in Angelica Sinensis root are a group of coumarin derivatives including oxypeucedanin, osthole, imperatorin, psoralen, and bergaptin.

How does Angelica Sinensis root extract powder work?

The applicable part of Angelica Sinensis root is the root. Angelica Sinensis root root has several active constituents. Some of these include ferulic acid, ligusticide, angelicide, brefeldin A, butylphthalide, nicotinic acid, and succinic acid. Angelica Sinensis root root contains a variety of other constituents including n-valerophenone-O-carboxylic acid, uracil, adenine, carvacrol, safrole, isosafrole, sesquiterpenes, n-dodecanol, n-tetradecanol, palmitic acid, angelic acid, myristic acid, and others.
The Angelica Sinensis root root also contains several vitamins and minerals including vitamin A, carotenoids, vitamin E, vitamin C, vitamin B12, biotin, folic acid, calcium, magnesium, and phytosterols such as beta-sitosterol (15109). It also contains 0.4% to 0.7% volatile oil.

Angelica Sinensis root also contains several coumarin constituents, however, there has been some debate about which coumarins are present in Angelica Sinensis root root. Some coumarins reported to be present in the root include angelol, angelicone, osthol, psoralen, oxypeucedanin, and bergapten. Some coumarins can act as vasodilators and antispasmodics. Osthol appears to inhibit platelet aggregation and smooth muscle contraction, and cause hypotension. Psoralen and bergapten are photosensitizing and can cause severe photodermatitis. Bergapten and other Angelica Sinensis root constituents, such as safrole and isosafrole, are carcinogenic.

Therapeutic pharmacologic activity is most often attributed to the ferulic acid and ligusticide constituents. Ferulic acid and ligusticide are sometimes used as marker compounds to assess Angelica Sinensis root root quality. The amount of these constituents in Angelica Sinensis root root can vary significantly from region to region.
Ferulic acid content usually ranges from 0.211-1.43 mg/gram of Angelica Sinensis root root. Ferulic acid is thought to have a wide variety of activities including antioxidant, anti-inflammatory, immunostimulant, antiarrhythmic and antiplatelet effects.

Ligusticide content ranges from about 4-14 mg/gram of Angelica Sinensis root root. The ligusticide constituent is thought to have antispasmodic and antiasthmatic effects. Angelica Sinensis root also contains a low molecular weight polysaccharide that shows anti-tumor activity in animals.

Some research suggests that Angelica Sinensis root root does not have estrogenic effects and therefore is not a phytoestrogen. However, other research suggests that it does have estrogenic effects. A Angelica Sinensis root extract competitively inhibits estradiol binding to estrogen receptors and induces transcription activity in estrogen-responsive cells. The ferulic acid constituent seems to have estrogenic activity. Ferulic acid stimulates proliferation of estrogen-receptor positive breast cancer cells in vitro. It also appears to up-regulate transcription of HER2 oncogene and ESR1 gene. A water-soluble extract of Angelica Sinensis root stimulates proliferation of both estrogen-receptor positive and negative breast cancer cells in vitro. The effect on estrogen-receptor positive cells appears to involve estrogen agonist activity. The effect on estrogen-receptor negative cells is independent of estrogen.

Preliminary research suggests Angelica Sinensis root might protect against ischemia-reperfusion injury.
Research in animal models also suggests that Angelica Sinensis root might help protect against endotoxemia and experimental sepsis. Dong qui might help reduce accumulation of inflammatory cytokines.
A multi-ingredient preparation containing Angelica Sinensis root is thought to work in premature ejaculation by increasing the penile vibratory threshold and reducing the amplitude of penile somatosensory evoked potentials.

Benefits of Angelica Sinensis root extract powder

Angelica Sinensis root is a traditional Chinese herbal remedy that is growing more popular here in the Western world. Why it's gaining popularity has much to do with the tremendous benefits for both men and women. In fact, Angelica Sinensis root has been touted as a cure for infertility, hot flashes and maybe even cancer. The key benefits are summarized as below:

1. Improves Female Fertility
Just an era ago infertility was uncommon, but these days we see it quite often. In many cases all that one needs is to switch their diet to an antifungal diet and to start taking this herb, and yet people still frequently seek the aid of costly fertility experts and undergo painful methods.

2. Boosts male fertility.

Ferulic acid, an antioxidant found in Angelica Sinensis root, has been shown to improve sperm quality.

3.Balances estrogen levels.

Angelica Sinensis root is the premier "gynecological regulator." It has the ability to reduce your estrogen levels if they are too high and can increase them if they are too low.

4.Excellent blood tonic.

 Master herbalist, Ron Teeguarden, attributes the blood toning and nourishing effects of Angelica Sinensis root to its amazing vitamin and mineral content. Angelica Sinensis root contains vitamin B 12, folic acid, folinic acid, nicotinic acid, and biotin.

Angelica Sinensis root is helpful after any injury or surgery to replenish your red blood cells and increase blood volume. It's included in nearly all Chinese herbal blood-building formulas.

5.benefits for women’s health

Angelica Sinensis root, derived from the root of the Chinese perennial Angelica sinensis, ranks just below ginseng as the most popular herb in China and Japan. It has often been referred to as the "female ginseng," popular among women for centuries as a "blood tonic" and used to promote a healthy menstrual cycle and to ease normal menstrual discomfort.

Currently, one of the most popular uses for angelica sinensis is as a treatment during and aftermenopause. It has been celebrated by herbalists for containing phytoestrogens, which may help replace missing estrogen and make less noticeable some of the symptoms of menopause. As previously mentioned, these claims are not verified by the traditional medical community and it is unclear that Angelica Sinensis root is of any use.

Side effects of Angelica Sinensis root extract powder

Angelica Sinensis root is generally considered to be quite safe when used properly. Angelica Sinensis root is not recommended for pregnant or breast-feeding women. Because the root contains chemicals called psoralens, Angelica Sinensis root may cause some fair-skinned people to become more sensitive to sunlight. Angelica Sinensis root should not be used by those who have chronic diarrhea or abdominal bloating. The essential oil of Angelica Sinensis root contains a small amount of cancer-causing substances, so driking directly drinking is not recommended. Men with prostate cancer and women with endometriosis, breast cancer, or cancers of the uterus or ovaries should not take Angelica Sinensis root. Angelica Sinensis root may increase the anti-clotting effects of prescription anticoagulants and antiplatelet agents, aspirin, and other herbal products.