Bladderwrack Extract (Fucus vesiculosus)

• Product Detail

Product name	Bladderwrack Extract (Fucus vesiculosus)
Latin Name	Fucus vesiculosus
Active ingredients	Saltagae Sterol , Fucosterol
synonyms	Arándano, Bleuet, Bleuet des Champs, Bleuet des Montagnes, Bleuets, Blueberries, Highbush Blueberry, Hillside Blueberry, Lowbush Blueberry, Myrtille, Rabbiteye Blueberry, Vaccinium altomontanum, Vaccinium amoenum, Vaccinium angustifolium, Vaccinium ashei, Vaccinium brittonii, Vaccinium constablaei, Vaccinium corymbosum, Vaccinium lamarckii, Vaccinium pallidum, Vaccinium pensylvanicum, Vaccinium vacillans, Vaccinium virgatum.
Appearance	Light Brown fine powder
Part used	Whole plant
Specification	4:1 TLC (100% water extraction） / 5:1 TLC (100% water extraction) / 10:1 TLC (100% Water extraction) / Saltagae Sterol 0.2% GC / Fucosterol 0.2% UV / Fucosterol 1.5% UV / Fucosterol 5% UV
Main benefits	Obesity and Diabetes ,anticancer, anti-diabetes
Applied industries	Medicine, food additive, dietary supplement

What is Bladderwrack Extract (Fucus vesiculosus)?

 Bladder wrack is named for its conspicuous vesicles.Fucus vesiculosus, known by the common names bladder wrack, black tang, rockweed, bladder fucus, sea oak, black tany, cut weed, dyers fucus, red fucus, and rock wrack is a seaweed found on the coasts of the North Sea, the western Baltic Sea, and the Atlantic and Pacific Oceans. It was the original source of iodine, discovered in 1811, and was used extensively to treat goitre, a swelling of the thyroid gland related to iodine deficiency.

The fronds of F. vesiculosus grow to 90 centimetres (35 in) long and 2.5 centimetres (1.0 in) wide and have a prominent midrib throughout. It is attached by a basal disc-shaped holdfast. It has almost spherical air bladders which are usually paired, one on either side of the mid-rib, but may be absent in young plants. The margin is smooth and the frond is dichotomously branched. It is sometimes confused with Fucus spiralis with which it hybridises and is similar to Fucus serratus[6]

Chemical constituents of Bladderwrack Extract (Fucus vesiculosus)

   Primary chemical constituents of this organism include mucilage, algin, mannitol, fucitol, beta-carotene, zeaxanthin, iodine, bromine, potassium, volatile oils, and many other minerals.

Benefits of taking Bladderwrack Extract (Fucus vesiculosus)  supplements:

1. Weight Loss and diabetes

  Fucus vesiculosus, stood out for its superior phenolic content, which was reflected by its high antioxidant ability and inhibition towards α-glucosidase activity (0.032 mg/mL of hydroacetonic extract inhibited 50% of the enzyme activity) [1]

2. Cancer Treatment

   the induction of autophagy and apoptosis on breast, endometrial and ovarian cancer cell lines suggests additional anti-tumorigenic actions of Fucus vesiculosus extract that are independent of ER status in female cancers[2]

3. Antimicrobial activit

   Certain sulfated polysaccharides from marine algae exert antimicrobial activities against human bacterial pathogens in addition to their physiological benefits. Among the sulfated polysaccharides, a fucoidan from Fucus vesiculosus showed notable antimicrobial activities against the selected dental plaque bacteria, including some foodborne pathogenic bacteria[3]

4. biological effects

 Fucaceae is the most dominant algae family along the intertidal areas of the Northern Hemisphere shorelines, being part of human customs for centuries with applications as a food source either for humans or animals, in agriculture and as remedies in folk medicine. These macroalgae are endowed with several phytochemicals of great industrial interest from which phlorotannins, a class of marine-exclusive polyphenols, have gathered much attention during the last few years due to their numerous possible therapeutic properties. These compounds are very abundant in brown seaweeds such as Fucaceae and have been demonstrated to possess numerous health-promoting properties, including antioxidant effects through scavenging of reactive oxygen species (ROS) or enhancement of intracellular antioxidant defenses,stimulation of adipocytes glucose uptake and protection of β-pancreatic cells against high-glucose oxidative stress; anti-inflammatory effects through inhibition of several pro-inflammatory mediators; antitumor properties by activation of apoptosis on cancerous cells and metastasis inhibition, among others. [4]

Side effects and safety of Bladderwrack Extract (Fucus vesiculosus)

Has not yet been reported that he has serious side effects.

It's certified safe by animal test[5]

References

[1]https://www.ncbi.nlm.nih.gov/pubmed/?term=Screening+of+Ulva+rigida%2C+Gracilaria+sp.%2C+Fucus+vesiculosus+and+Saccharina+latissima+as+Functional+Ingredients

[2]https://www.ncbi.nlm.nih.gov/pubmed/?term=A+Fucus+vesiculosus+extract+inhibits+estrogen+receptor+activation+and+induces+cell+death+in+female+cancer+cell+lines.

[3]https://www.ncbi.nlm.nih.gov/pubmed/?term=Antimicrobial+and+Antibiofilm+Activities+of+Sulfated+Polysaccharides+from+Marine+Algae+against+Dental+Plaque+Bacteria.

[4]https://www.ncbi.nlm.nih.gov/pubmed/?term=Fucaceae%3A+A+Source+of+Bioactive+Phlorotannins.

[5]https://www.ncbi.nlm.nih.gov/pubmed/?term=Safety+evidence+on+the+administration+of+Fucus+vesiculosus+L.+(bladderwrack)+extract%3A+data+from+pharmacokinetic+studies+in+the+rat

[6]https://en.wikipedia.org/wiki/Fucus_vesiculosus