Poke Root Extract

• Product Detail

Product name	Poke Root Extract
Latin Name	Phytolacca decandra
Active ingredients	Phytolaccine
synonyms	Phytolacca Root. Phytolaccae Radix. Phytolacca Berry. Phytolaccae Bacca. Phytolacca Vulgaris. Phytolacca Americana. Blitum Americanum. Branching Phytolacca. Phytolaque. Garget. Pigeon Berry. Méchoacan du Canada. Bear's Grape. Poke Weed. Raisin d'Amérique. Red-ink Plant. American Spinach. Skoke. Crowberry. Jalap. Cancer-root. American Nightshade. Pocan or Cokan. Coakum. Chongras. Morelle à Grappes. Herbe de la Laque. Amerikanische scharlachbeere. Kermesbeere. Virginian Poke. Poke Berry
Appearance	Brown fine powder
Part used	Root
Specification	5:1 10:1 20:1
Dosage
Main benefits	Anticancer, Antiviral, weight loss
Applied industries	Medicine, food additive, dietary supplement, sports nutrition

What is Poke Root Extract?

Poke Root is a perennial that grows up-right and it has succulent stems that are red-flushed and it has pointed leaves that are ovate to lanceolate. In the summer it blooms small pinkish-white flowers in erect racemes which are followed by fleshy purplish-black berries in thick spikes.

Poke is an alterative, anodyne, antibiotic, anti-inflammatory, anti-rheumatic,anti-scorbutic, anti-syphilitic, anti-tumor, cathartic, emetic and parasiticide. The parts of the plant that are used in herbal healing are the berries and roots. Poke Root is a pungent bitter herb that stimulates the immune and lymphatic systems.

Poke root is traditionally used in Chinese medicine for water retention, sore throat, and abscesses.

Poke Root is very effective in fighting bacterial, fungal, parasitic and viral infections. It aids in the healing of mastitis, mononucleosis and mumps. When used in excess it can cause diarrhea and vomiting so use in small doses. It also works great in treating gingivitis and halitosis.

Chemical constituents of Poke Root Extract

Pokeberry root contains Phytolaccine and starch by about 25%. It is including the Esculentic acid, Phytolaccagenin A, B, C, 6 kinds of triterpenoid saponins. namely glucoside A, B, C, D, E, F, root, stem and leaf all contain the Phytolaccatoxin, Oxyristic acid, Jaligouic acid, saponins, and more quantity of potassium nitrate.also contains gamma-aminobutyric acid.

Benefits of taking Poke Root Extract supplements:

Treating Cancer with Poke Root

》Impact of Phytolacca americana Extracts on Gene Expression of Colon Cancer Cells.

Source

North Carolina Agricultural and Technical State University, Department of Family and Consumer Sciences, Food and Nutritional Sciences Program, Greensboro, NC, 27411, USA.

Abstract

Native Americans have used Phytolacca americana to treat breast ailments, gastrointestinal disorders, rashes, and inflammation. Some anti-cancer and anti-viral research has been reported on this perennial herb, but none has been published concerning the effects of its extracts on cancer cell genes. In this study, changes in gene expression at the transcription level were evaluated in HCT-116 colon cancer cells after exposure to P. americana ethanol extract and its water fraction using the Human Cancer Pathway Finder PCR Array. Of the genes significantly affected in HCT-116 cells exposed to the ethanol extract at 3200 µg/ml, changes in expression of MYC, PLAU, and TEK may benefit the treatment of colon cancer. Exposing the cells to 1600 µg/ml of the water fraction resulted in several gene changes that may also be beneficial in the treatment of colon cancer: NME4, TEK, and THBS1. A few genes on this array that are known to play a specific role in colon cancer had activities changed in a way that may be detrimental in the treatment of colon cancer. Further studies should be performed to understand how these changes would impact colon cancer treatment.

Antiviral

》Inhibition of Japanese encephalitis virus infection in vitro and in vivo by pokeweed antiviral protein.

Source

College of Veterinary Medicine, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu Province, 210095, PR China.

Abstract

Pokeweed antiviral protein (PAP) is a plant-derived N-glycosidase ribosomal-inactivating protein isolated from Phytolacca americana. The antiviral activity of PAP has been described in several viruses. This study was to investigate the antiviral activity of PAP against Japanese encephalitis virus (JEV) infection in vitro and in vivo. Antiviral activity of PAP against JEV infection was evaluated in vitro using plaque forming assay, qRT-PCR and Western blot analysis. In vitro results showed that PAP inhibited replication of JEV in a dose-dependent manner with 50% inhibitory concentration (IC(50)) of 300 ng/ml (23.1 nM). Depurination assay suggested that the antiviral activity of PAP against JEV infection might be partially due to depurination of JEV genomic RNA. In vivo studies showed that PAP (1.0mg/kg) administered intraperitoneally decreased infection in mice challenged with a lethal dose of JEV, presenting a survival of 87.5% or 85.7% when administered pre-infection or post-infection. Collectively, our studies demonstrated that PAP possesses antiviral activity against JEV infection in vitro and in vivo, providing evidences for further development of PAP as an antiviral agent against JEV infection.

Other uses

Abscesses, acne, arthritis, back pain, blood cleanser, boils, breasts disorders and problems, bronchitis, bursitis, cancer, catarrh, colds, cystitis, degenerative diseases, eczema, gingivitis, halitosis, hemorrhoids, inflammation, laryngitis, liver disorders and problems, lymph gland disorders and problems, mastitis, mononucleosis, mucus, mumps, pain, parasites, psoriasis, respiratory problems, rheumatism, scabies, scrofula, skin diseases, sores, tonsillitis, tumors, wounds and worms.

Side effects and safety of Poke Root Extract

The effects of eating the uncooked or improperly prepared plant can include nausea, vomiting, diarrhea, abdominal cramps, headaches, blurred vision, confusion, dermatitis, dizziness, and weakness.

The plant may cause menstrual cycle irregularities and may also stimulate contractions of the uterus. Women who are pregnant or breast-feeding should not use pokeweed.

Dosage of Poke Root Extract supplement:

As emetic, 10 to 30 grains. As alterative, 1 to 5 grains. Of fluid extract of berries, 1/2 to 1 drachm. Of fluid extract of root, 1/4 to 1/2 drachm; as an emetic, 15 drops; as an alterative, 2 drops. Phytolaccin, 1 to 3 grains.

Company Information:

Nutragreen Biotechnology Co., Ltd, a brand of Shanghai Lvshang Biotech Co., Ltd, is a GMP compliant and FDA registered manufacturer and supplier of raw materials of plant extracts, botanicals, herbs, especially Tradtional Chinese herbs. Poke Root Extract is one of our most competitive ingredients with various specifications and stocks available all year round. You may leave a message below for more detailed information.