Cassia Nomame Extract powder |
|
Latin Name |
Cassia mimosoides L. |
Active ingredients |
Flavanols |
synonyms |
Nomame, fishbone cassia |
Appearance |
Dark Brown-Yellow fine powder |
Part used |
Herb |
Specification |
Flavanols 8% UV |
Dosage |
|
Main benefits |
weight loss |
Applied industries |
Medicine, food additive, dietary supplement, sports nutrition |
What is Cassia Nomame Extract powder?
Cassia Nomame P.E. is a source in the natural product industry to help people with weight problems by using its lipase inhibition activity to prevent the fat absorption. This time in a natural fashion, the mechanism of lipase inhibition demonstrated by a new OTC pharmaceutical has already been marketed.
How dose work
Cassia nomame is able to block
the absorption of fat into your bloodstream by impairing the enzyme that makes
fat breakdown possible. So these fat molecules remain whole, and your body does
not even gain calorie content from them. They continue through our system and
are eliminated as waste.
Lipase inhibitors are proving
significantly effective in the weight loss area. Many double blind studies
conducted in both the US and Europe tested thousands of people. Reports are
showing lipase inhibitors block up to 30% of the fat ingested. Studies at PKU
China report a 28% inhibition of fats (lipase) absorbed.
Benefits of taking Cassia Nomame Extract powder supplements:
Natural
lipase inhibitors
Two studies support the use of echinacea for this
purpose.
》Flavan dimers with lipase inhibitory activity from Cassia nomame
(Faculty of Pharmaceutical Sciences, Okayama University, Tsushima,
Okayama 700, Japan)
Five flavan dimers which showed lipase-inhibiting effects were isolated from fruits of Cassia nomame (Leguminosae). Structures of two new compounds among them were determined to be (2S)-3′,4′,7-trihydroxyflavan-(4β → 8)-catechin and (2S)-3′,4′,7-trihydroxyflavan-(4α → 8)-catechin. Fouf flavan dimers structurally related to these two compounds were also synthesized for spectral comparison. Among 10 flavan dimers tested for lipase-inhibitory activity, (2S)-3′,4′,7-trihydroxyflavan-(4α → 8)-catechin showed the most potent inhibitory effect. A partially purified fraction composed of oligomeric flavans with Mn 1020 also showed a noticeable inhibitory effect.
》Anti-obesity effects of lipase inhibitor CT-II, an extract from
edible herbs, Nomame Herba, on rats fed a high-fat diet.
Source
Department of Biotechnology, Lotte Co. Ltd,
3-1-1 Numakage, Urawa-shi, Saitama, Japan.
Abstract
DESIGN:
The assay for the inhibitory effect of
CT-II on lipase activity was performed by measuring released free fatty acids
after the incubation of the medium with CT-II, porcine pancreatic lipase and
triolein (experiment 1). In vivo experiments, lean rats or obese rats (570-718
g) were fed a high-fat diet containing 60% fat with or without CT-II for 8
weeks (experiment 2), for 14 days (experiment 3) or for 12 weeks (experiment
4), respectively.
MEASUREMENT:
The time course of body weight, food
intake, organ weight (parametrial fat, liver, heart and kidney) and plasma
parameters (triglyceride, total cholesterol, glucose, AST, ALT and insulin),
fecal output of total fat and total cholesterol were measured. Hepatic
histological examinations were also performed.
RESULTS:
CT-II inhibited the porcine lipase activity
dose-dependently in vitro (experiment 1). Body and liver weight were reduced
and hepatic histological examination showed an amelioration of fatty liver in
CT II treated animals (experiment 2). CT-II significantly inhibited body weight
gain and plasma triglyceride elevation in a dose-dependent manner, without
affecting food intake in lean rats fed the high-fat diet. Elevated plasma AST
and ALT were also decreased (experiment 3). When obese rats fed the high-fat
diet were treated with CT-II for up to 6 months, body weight was initially
reduced and thereafter weight gain was significantly suppressed. Total body fat
was also significantly reduced and significant reduction of plasma AST and ALT
was observed (experiment 4).
These results demonstrated that the lipase inhibitor CT-II is effective in preventing and ameliorating obesity, fatty liver and hypertriglyceridemia in rats fed a high-fat diet.
Other use
All the grass medicine, treat night blindness, eye ", migraine;Seed diuresis, lack; To Gan disease polio, night blindness, eye --beriberi, jaundice. Leaves shanghai.by tea; Root leaf nitrogen is rich, perishable quality is covered.
Side effects and safety of Cassia Nomame Extract powder
People a lot of take can cause diarrhea, pregnant women eat more there had a miscarriage.
Dosage of Cassia Nomame Extract powder supplement:
Consult your physician if you have any questions about the proper use of Cassia Nomame Extract supplements.