Burdock Root Extract powder

• Product Detail

Product name	Burdock Root Extract powder
Latin Name	Arctium Lappa L.
Active ingredients	Arctiin
synonyms	Arctium, Arctium lappa, Arctium minus, Arctium tomentosum, Bardana, Bardana-minor, Bardanae Radix, Bardane, Bardane Comestible, Bardane Géante, Bardane Majeure, Beggar's Buttons, Burdock Root Extract, Burr Seed, Clotbur, Cocklebur, Cockle Buttons, Edible Burdock, Fox's Clote, Gobo, Glouteron, Grande Bardane, Great Bur, Great Burdocks, Happy Major, Hardock, Harebur, Herbe aux Teigneux, Herbe du Teigneux, Lappa, Love Leaves, Niu Bang Zi, Orelha-de-gigante, Personata, Philanthropium, Rhubarbe du Diable, Thorny Burr.
Appearance	Brown fine powder
Part used	Root
Specification	10:1 ,Arctiin 2% , Arctiin 10%
Dosage
Main benefits	Antioxidant, anticancer, Diuretic
Applied industries	Medicine, food additive, dietary supplement, sports nutrition

What is Burdock Root Extract powder?

Burdock is a perennial whose roots, leaves, and sometimes its seeds are used widely in herbal medicine to support liver function and as a cleansing botanical. Like dandelion and yellow dock, burdock roots are bitter and thus capable of stimulating digestive secretions and aiding digestion. These roots are referred to as "alterative" agents -- capable of enhancing digestion and the absorption of nutrients and supporting the elimination of wastes. Any botanical capable of these important actions can attain far-reaching improvements in a variety of complaints.

Burdock Root contains a number of medicinal properties that have been used for hundreds of years.  Traditionally herbalists all over the world use Burdock Root as a blood purifier.  It is the root of the Burdock plant that is harvested for folk medicinal use.

Chemical constituents of Burdock Root Extract powder

Burdock root yields a wide variety of compounds on analysis that include inulin (up to 50%), tannins, polyphenolic acids (caffeic and chlorogenic), volatile acids (acetic, butyric, costic, 3-hexenoic, isovaleric, 3-octanoic, propionic, etc), polyacetylenes (0.001% to 0.002%, dry-weight basis), and a crystalline plant hormone, gamma-guanidino-n-butyric acid. Studies conducted have isolated and characterized a xyloglucan from the 24% KOH extract of edible burdock. The seeds of burdock yield 15% to 30% fixed oils; a bitter glycoside (arctiin), two lignans (lappaols A and B), chlorogenic acid, a germacranolide and other materials. Other studies have isolated six compounds from burdock seeds including daucosterol, arctigenin, arctiin, matairesinol, lappaol and a new lignan named neoarctin. The levels of arctiin and arctigen in the fruits of burdock that are used in Chinese medicine for the treatment of common colds have also been studied. 5Others have also reported on the fruit constituents, and even the fruit pulp (pomace). The fruit pulp contains 11% proteins, 19% lipids and 34% inulin.

Benefits of taking Burdock Root Extract powder supplements:

Traditional medicine

Burdock has been used by herbalists worldwide to treat a variety skin diseases such as abscesses, acne, carbuncles, psoriasis and eczema.    Burdock can be either taken alone or combined with other remedies, such as Yellow Dock and Sarsaparilla.    The beneficial effects of this herb includes increasing circulation to the skin, helping to detoxify the epidermal tissues.   Burdock Root has been reported to destroy bacteria and fungus cultures.  It is a popular detoxifying agent that produces a diuretic effect on the body which aids the filtering of impurities from the bloodstream.   By promoting perspiration, Burdock Root eliminates toxins through the skin.   By producing a detoxifying effect, Burdock Root aids blood circulation and produces a variety of positive side effects.  As before mentioned, it contains inulin, a carbohydrate that strengthens the liver.    The high concentration of inulin and mucilage aids in the soothing effects on the gastrointestinal tract. The high concentration of inulin is helpful for individuals that are afflicted with diabetes and hypoglycemia as it provides helpful sugar that does not provoke rapid insulin production.   Inulin, which is very high in Burdock, is a resinoid or camphor-like hydrocarbon that is aromatic, stimulant, expectorant, tonic, stomachic, and antiseptic.

Modern Medicine

Improves sexual activity

>Effect of aqueous extract of Arctium lappa L. (burdock) roots on the sexual behavior of male rats.

 (Source-School of Life Sciences, Shandong University, Jinan 250100, PR China.)

Abstract

BACKGROUND:

Arctium lappa L. root has traditionally been recommended as an aphrodisiac agent. It is used to treat impotence and sterility in China, and Native Americans included the root in herbal preparations for women in labor. However, its use has not been scientifically validated. The present study therefore investigated the effects of aqueous extract of Arctium lappa L. roots on sexual behavior in normal male rats.

METHODS:

Seventy-five albino male rats were randomly divided into five groups of 15 rats each. Rats in group 1 (control) were administered 10 mL/kg body weight distilled water (vehicle), group 2 received 60 mg/kg body weight sildenafil citrate (Viagra), while those in groups 3, 4, and 5 were given 300, 600, and 1,200 mg/kg body weight, respectively, of aqueous extract of Arctium lappa L. roots in the same volume. Female albino rats were made receptive by hormonal treatment. Sexual behavior parameters in male rats were monitored on days 3, 7 and 15 by pairing with receptive females (1:3). Male serum testosterone concentrations and potency were also determined.

RESULTS:

Oral administration of Arctium lappa L. roots extract at 600 and 1,200 mg/kg body weight significantly increased the frequencies of mount, intromission, and ejaculation frequency (p < 0.05). The latencies of mount and intromission were significantly reduced and ejaculation latency was prolonged. Administration of the extract also reduced the post-ejaculatory interval. The standard drug (Viagra) was more effective than the extract. The extract significantly increased the frequencies of all components of penile reflexes as well as serum testosterone levels, compared with the distilled water controls.

CONCLUSIONS:

The results of this study demonstrate that aqueous extract of Arctium lappa L. roots enhances sexual behavior in male rats. The aphrodisiac effects of the plant extract may be related to the presence of flavonoids, saponins, lignans and alkaloids, acting via a multitude of central and peripheral mechanisms. These results thus support the traditional use of Arctium lappa L. root extract for treating impotence and sterility.

Burdock and inflammation

Arctigenin ameliorates inflammationin vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.

Hyam SR, Lee IA, Gu W, Kim KA, Jeong JJ, Jang SE, Han MJ, Kim DH.

Source

Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, Kyung Hee University, Seoul 130-701, Republic of Korea.

Abstract

Seeds of Arctium lappa, containing arctigenin and its glycoside arctiin as main constituents, have been used as a diuretic, anti-inflammatory and detoxifying agent in Chinese traditional medicine. In our preliminary study, arctigenin inhibited IKKβ and NF-κB activation in peptidoglycan (PGN)- or lipopolysaccharide (LPS)-induced peritoneal macrophages. To understand the anti-inflammatory effect of arctigenin, we investigated its anti-inflammatory effect in LPS-stimulated peritoneal macrophages and on LPS-induced systemic inflammation as well as 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice. Arctigenin inhibited LPS-increased IL-1β, IL-6 and TNF-α expression in LPS-stimulated peritoneal macrophages, but increased LPS-reduced IL-10 and CD204 expression. Arctigenin inhibited LPS-induced PI3K, AKT and IKKβ phosphorylation, but did not suppress LPS-induced IRAK-1 phosphorylation. However, arctigenin did not inhibit NF-κB activation in LPS-stimulated PI3K siRNA-treated peritoneal macrophages. Arctigenin suppressed the binding of p-PI3K antibody and the nucleus translocation of NF-κB p65 in LPS-stimulated peritoneal macrophages. Arctigenin suppressed blood IL-1β and TNF-α level in mice systemically inflamed by intraperitoneal injection of LPS. Arctigenin also inhibited colon shortening, macroscopic scores and myeloperoxidase activity in TNBS-induced colitic mice. Arctigenin inhibited TNBS-induced IL-1β, TNF-α and IL-6 expression, as well as PI3K, AKT and IKKβ phosphorylation and NF-κB activation in mice, but increased IL-10 and CD204 expression. However, it did not affect IRAK-1 phosphorylation. Based on these findings, arctigenin may ameliorate inflammatory diseases, such as colitis, by inhibiting PI3K and polarizing M1 macrophages to M2-like macrophages.

Burdock and antioxidant

>Ethanolic extract of roots from Arctium lappa L. accelerates the healing of acetic acid-induced gastric ulcer in rats: Involvement of the antioxidant system.

(Source-Department of Pharmacology, Federal University of Parana, Curitiba, PR, Brazil.)

Abstract

We evaluate the curative efficacy of the ethanolic extract (EET) of roots from Arctium lappa (bardana) in healing of chronic gastric ulcers induced by 80% acetic acid in rats and additionally studies the possible mechanisms underlying this action. Oral administration of EET (1, 3, 10 and 30mg/kg) reduced the gastric lesion area in 29.2%, 41.4%, 59.3% and 38.5%, respectively, and at 10mg/kg promoted significant regeneration of the gastric mucosa, which was confirmed by proliferating cell nuclear antigen immunohistochemistry. EET (10mg/kg) treatment did not increase the gastric mucus content but restored the superoxide dismutase activity, prevented the reduction of glutathione levels, reduced lipid hydroperoxides levels, inhibited the myeloperoxidase activity and reduced the microvascular permeability. In addition, EET reduced the free radical generation and increased scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals in vitro. Furthermore, intraduodenal EET (10 and 30mg/kg) decreased volume and acidity of gastric secretion. Total phenolic compounds were high in EET (Folin-Ciocalteau assay) and the analysis by liquid chromatography-mass spectrometry revealed that the main compounds present in EET were a serie of hydroxycinnamoylquinic acid isomers. In conclusion, these data reveal that EET promotes regeneration of damaged gastric mucosa, probably through its antisecretory and antioxidative mechanisms.

Burdock and skin

Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L.

(Source-Department of Pediatrics, College of Medicine, Hanyang University, Seoul, 133-792, Korea. )

Abstract

BACKGROUND:

Atopic dermatitis is a chronic, allergic inflammatory skin disease that is accompanied by markedly increased levels of inflammatory cells, including eosinophils, mast cells, and T cells. Arctium lappa L. is a traditional medicine in Asia. This study examined whether a butanol extract of A. lappa (ALBE) had previously unreported anti-allergic or anti-inflammatory effects.

METHODS:

This study examined the effect of ALBE on the release of β-hexosaminidase in antigen-stimulated-RBL-2H3 cells. We also evaluated the ConA-induced expression of IL-4, IL-5, mitogen-activated protein kinases (MAPKs), and nuclear factor (NF)-κB using RT-PCR, Western blotting, and ELISA in mouse splenocytes after ALBE treatment.

RESULTS:

We observed significant inhibition of β-hexosaminidase release in RBL-2H3 cells and suppressed mRNA expression and protein secretion of IL-4 and IL-5 induced by ConA-treated primary murine splenocytes after ALBE treatment. Additionally, ALBE (100 μg/mL) suppressed not only the transcriptional activation of NF-κB, but also the phosphorylation of MAPKs in ConA-treated primary splenocytes.

CONCLUSIONS:

These results suggest that ALBE inhibits the expression of IL-4 and IL-5 by downregulating MAPKs and NF-κB activation in ConA-treated splenocytes and supports the hypothesis that ALBE may have beneficial effects in the treatment of allergic diseases, including atopic dermatitis.

Other use

>Diuretic (increases urination)

>Skin care and conditions including acne, eczema and psoriasis

>Treat bacterial skin infections (boils, abscesses)

>Treat sore throat and cold

>Decongestant

>Hair and scalp conditioning (hair growth)

>Laxative

>Depurative (purifying blood)

>Anti-oxidant

>Immune Stimulation

>Promotes hepatic function

>Promotes weight loss

>Lowers blood sugars

>Improves lipid profiles

>Reduces heart disease and stroke

>Anti-inflammatory treats gout.

>Decreases platelet stickiness (decreases blood viscosity)

>Anti-tussive (cough suppressant)

>Treats stomach upset and pain (irritable bowel syndrome)

>Antipyretic: (lowers fever)

>Anti-cancer properties with proven scientific study in certain cancers.

>Anti-HIV

>Treats fungal infection

>Stimulates uterine contractions

>Treats kidney stones

>Treats gallstones

Side effects and safety of Burdock Root Extract powder

Burdock is safely used as a food in Asia. There is no report has serious side effects.

Dosage of Burdock Root Extract powder supplement:

It is safe, according to need to adjust the quantity

Company Information:

Nutragreen Biotechnology Co., Ltd, a brand of Shanghai Lvshang Biotech Co., Ltd, is a GMP compliant and FDA registered manufacturer and supplier of raw materials of plant extracts, botanicals, herbs, especially Tradtional Chinese herbs. Burdock Root Extract powder is one of our most competitive ingredients with various specifications and stocks available all year round. You may leave a message below for more detailed information.